What is causing a mysterious brain illness in Karachi, Pakistan's teeming and unruly commercial capital?

Neurologist Asad Mirza, freshly returned from training in the United States, and Nadia Khan, an ambitious young medical student, find themselves confronting this riddle in the wards of Avicenna University Hospital.

 And what is the cause - an infection, a poison or something else, something utterly weird? As the  duo begins piecing together the puzzle, sinister clues appear. Soon, a terrifying picture emerges pointing to a heinous plot that could have unimaginable consequences for none other than the United States of America, a country for which almost everyone has mixed feelings. The stakes are sky-high and time is running extremely short . . .